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DeCS
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Descriptor English:
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Autophagy-Related Protein 12
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Descriptor Spanish:
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Proteína 12 Relacionada con la Autofagia
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Descriptor Portuguese:
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Proteína 12 Relacionada à Autofagia
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Synonyms English:
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ATG12 Protein
ATG12, Ubiquitin-Like Protein
Autophagy Related Protein 12
Ubiquitin Like Protein ATG12
Ubiquitin-Like Protein ATG12
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Tree Number:
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D12.776.094.391
D12.776.947.125
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Definition English:
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A UBIQUITIN-like modifier protein that functions in AUTOPHAGOSOME formation, CYTOPLASM to VACUOLE transport, MITOPHAGY, and nucleophagy. Conjugation with ATG5 PROTEIN or ATG10 is essential for its function. The ATG12-ATG5 conjugate acts as an E3 UBIQUITIN LIGASE-like enzyme for lipid modification of ATG8 FAMILY PROTEINS and their localization to vesicle membranes. |
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History Note English:
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2017
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Allowable Qualifiers English:
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Record Number:
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56558
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Unique Identifier:
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D000071192
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Occurrence in VHL:
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Similar:
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DeCS
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